Article

Integrating epigenomic features reveals principles of chromatin-state organization

2026-07-23

Abstract excerpt

The coordinated activities of histone modifications and chromatin-associated proteins establish chromatin states that regulate genome function and cellular identity. However, the organizational principles that distinguish chromatin states across cell types remain incompletely understood. Here, we integrated genome-wide profiles of CTCF, H3K27ac, H3K9ac, H3K27me3, and H3K9me3 at 1-kb resolution to generate a unifie...

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Literature Corpus work: f899fa07-b570-5dee-82d0-2120b339e447
DOI: 10.64898/2026.07.23.740373

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