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Insight into origins, mechanisms, and utility of DNA methylation in B-cell malignancies

23 Jul 2018

Abstract excerpt

Understanding how tumor cells fundamentally alter their identity is critical to identify specific vulnerabilities for use in precision medicine. In B-cell malignancy, knowledge of genetic changes has resulted in great gains in our understanding of the biology of tumor cells, impacting diagnosis, prognosis, and treatment. Despite this knowledge, much remains to be explained as genetic events do not completely...

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PMID: 30037886
DOI: 10.1182/blood-2018-02-692970

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