Article

Cold Exposure Protects from Neuroinflammation Through Immunologic Reprogramming

2020-08-30

Abstract excerpt

<h4>SUMMARY</h4> Autoimmunity is energetically costly, but the impact of a metabolically active state on immunity and immune-mediated diseases is unclear. Ly6C hi monocytes are key effectors in CNS autoimmunity with elusive role in priming naïve autoreactive T cells. Here we provide unbiased analysis of the immune changes in various compartments during cold exposure, and show that this energetically costly stimu...

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Literature Corpus work: 59c648bb-5bbd-561e-9843-ee2a74126aef
DOI: 10.1101/2020.08.28.269563

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