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Article

Influence of heat stress on human monocyte-derived dendritic cell functions with immunotherapeutic potential for antitumor vaccines.

Journal of leukocyte biology - 1 May 2007

Hatzfeld-Charbonnier Anne Sophie, Lasek Audrey, Castera Laurent, Gosset Philippe, Velu Thierry, Formstecher Pierre, Mortier Laurent, Marchetti Philippe

Abstract excerpt

Mild heat stress can modulate the activities of immune cells, including dendritic cells (DC) and theoretically, would constitute an innovative approach capable of enhancing the antitumor functions of DC. Therefore, we tested the effects of mild heat stress on the physiology and viability of human monocyte-derived DC, the major type of DC used in tumor immunotherapy trials. We first designed a heat-stress protocol...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17311933
DOI: 10.1189/jlb.0506347
PMCID: PMC2254491

Genes

CCL19
MIP
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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