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Article

Plasticity of Ly-6C(hi) myeloid cells in T cell regulation.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2011

Zhu Bing, Kennedy Jennifer K, Wang Yue, Sandoval-Garcia Carolina, Cao Li, Xiao Sheng, Wu Chuan, Elyaman Wassim, Khoury Samia J

Abstract excerpt

CD11b(+)Ly-6C(hi) cells, including inflammatory monocytes (IMCs) and inflammatory dendritic cells (IDCs), are important in infectious, autoimmune, and tumor models. However, their role in T cell regulation is controversial. In this article, we show that T cell regulation by IMCs and IDCs is determined by their activation state and is plastic during an immune response. Nonactivated IMCs and IDCs function as APCs,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21824867
DOI: 10.4049/jimmunol.1100403
PMCID: PMC3159773

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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