Article

AMP-activated protein kinase is essential for the maintenance of energy levels during synaptic activation

2018-04-30

Abstract excerpt

While accounting for 2% of the total body mass, the brain is the organ that consumes the most energy. Although it is widely acknowledged that neuronal energy metabolism is tightly regulated, the mechanism how neurons meet their energy demand to sustain synaptic transmission remains poorly studied. Here we provide substantial evidence that the AMP-activated protein kinase (AMPK) plays a leading role in this process...

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Literature Corpus work: 591551e9-ff67-54ea-8820-c9923fe7ef8f
DOI: 10.1101/303867

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