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Age‐related AMP‐activated protein kinase alterations: From cellular energetics to longevity

21 Mar 2019

Abstract excerpt

5' adenosine monophosphate-activated protein kinase (AMPK) is a key regulator of energy in the cell, which allows the cell/organism to survive with deficit of ATP. Since AMPK is involved in the adaptation to caloric restriction, the role of age-related changes in AMPK activity in both the aging organism and the aging cell is actively investigated in gerontology. Studies on yeast, worms, flies, rodents, and...

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PMID: 30895648
DOI: 10.1002/cbf.3384

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