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Fueling the Mind: Brain Metabolism in Health and Neurodevelopmental Disorders

3 Sept 2025

Abstract excerpt

The adult human brain, under resting conditions, consumes approximately 20% of total body glucose, a demand that is even higher during the first decade of life. The brain metabolic landscape is intricately regulated throughout development, and each cell type exhibits distinct metabolic signatures at each specific stage. This picture becomes even more intricate when considering that metabolism is dynamically...

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PMID: 40902207
DOI: 10.1146/annurev-genet-111523-102424

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