Article

Profiling of pluripotency factors in individual stem cells and early embryos

2018-03-21

Abstract excerpt

<h4>SUMMARY</h4> Major cell fate decisions are governed by sequence-specific transcription factors (TFs) that act in small cell populations within developing embryos. To understand how TFs regulate cell fate it is important to identify their genomic binding sites in these populations. However, current methods cannot profile TFs genome-wide at or near the single cell level. Here we adapt the CUT&RUN method to prof...

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Literature Corpus work: 5865d43d-8693-5174-aebd-0fc7b81f68a6
DOI: 10.1101/286351

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