Article

Human-specific genomic features of pluripotency regulatory networks link NANOG with fetal and adult brain development

2015-07-21

Abstract excerpt

Genome-wide proximity placement analysis of diverse families of human-specific genomic regulatory loci (HSGRL) identified topologically-associating domains (TADs) that are significantly enriched for HSGRL and termed rapidly-evolving in humans TADs (revTADs; Genome Biol Evol. 2016 8; 2774-88). Here, human-specific genomic features of pluripotency regulatory networks in hESC have been analyzed. The primary focus was...

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Literature Corpus work: 4477e6d5-4831-5b22-b829-9a2854b29d1c
DOI: 10.1101/022913

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