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Article

Host Cell Transcriptome Profile during Wild-Type and Attenuated Dengue Virus Infection

14 Mar 2013

Abstract excerpt

Dengue viruses 1-4 (DENV1-4) rely heavily on the host cell machinery to complete their life cycle, while at the same time evade the host response that could restrict their replication efficiency. These requirements may account for much of the broad gene-level changes to the host transcriptome upon DENV infection. However, host gene function is also regulated through transcriptional start site (TSS) selection and...

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PMID: 23516652
DOI: 10.1371/journal.pntd.0002107

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