Article

Defining specific cell states of MPTP-induced Parkinson’s disease by single-nucleus RNA sequencing

2022-05-30

Abstract excerpt

Parkinson’s disease (PD), a neurodegenerative disease with the impairment of movement execution that is related to age, genetic and environmental factors. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyri-dine (MPTP) is a neurotoxin widely used to induce PD models, but the effect of MPTP on cell-gene of PD has not been fully elucidated. By single-nucleus RNA sequencing, we uncovered the PD-specific cells and revealed remar...

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Literature Corpus work: 57eaa35b-6a8a-5f43-b6d0-b716416b14d0
DOI: 10.1101/2022.05.29.493938

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