Article

Sensitivity of DNA double-strand break loci is coupled with spatial interaction density of chromatin

2023-07-11

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> DNA double-strand breaks, one of the most serious types of damage to the genome, are closely related to chromatin rearrangement and oncogene activation. However, the mechanisms of DSB formation and repair upon the genome are still unclear. Recent advances in chromatin conformation capture technology Hi-C enable clear identification of the relationship between ch...

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Literature Corpus work: 574df339-e8aa-56d4-82e1-84f52065150c
DOI: 10.21203/rs.3.rs-3120397/v1

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