Article

Development and Comparative Evaluation of Endolysosomal Proximity Labeling-based Proteomic Methods in Human iPSC-derived Neurons

2020-09-16

Abstract excerpt

<h4>ABSTRACT</h4> Proximity-based in situ labeling techniques offer a unique way to capture both stable and transient protein-protein and protein-organelle interactions. Combining this technology with mass spectrometry (MS)-based proteomics allows us to obtain snapshots of molecular microenvironments with nanometer resolution, facilitating the discovery of complex and dynamic protein networks. However, a number...

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Literature Corpus work: 574b4533-dae8-51f5-a712-d6cea9ca7609
DOI: 10.1101/2020.09.15.298091

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