Article

Endo-IP and Lyso-IP Toolkit for Endolysosomal Profiling of Human Induced Neurons

2024-09-26

Abstract excerpt

Plasma membrane protein degradation and recycling is regulated by the endolysosomal system, wherein endosomes bud from the plasma membrane into the cytosol and mature into degradative lysosomes. As such, the endolysosomal system plays a critical role in determining the abundance of proteins on the cell surface, influencing cellular identity and function. Highly polarized cells, like neurons, rely on the endolysoso...

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Literature Corpus work: dc71ce4d-2e60-526e-b74b-5e4363de5ef7
DOI: 10.1101/2024.09.24.614704

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