Article

Identifying developing interneurons as a potential target for multiple genetic autism risk factors in human and rodent forebrain

2021-06-03

Abstract excerpt

<h4>ABSTRACT</h4> Autism spectrum condition or ‘autism’ is associated with numerous monogenic and polygenic genetic risk factors including the polygenic 16p11.2 microdeletion. A central question is what neural cells are affected. To systematically investigate we analysed single cell transcriptomes from gestational week (GW) 8-26 human foetal prefrontal cortex and identified a subset of interneurons (INs) first a...

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Literature Corpus work: 5739c4aa-8f6a-5bab-9840-a7353c129a98
DOI: 10.1101/2021.06.03.446920

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