Article

The <i>16p11.2</i> microdeletion enhances gene expression variability between human IPSC derived forebrain interneuron progenitor cells in culture

2026-05-24

Abstract excerpt

<h4>ABSTRACT</h4> The 574 kilobase pair 16p11.2 microdeletion raises a person’s odds for neurodevelopmental and energy balance conditions, particularly autism and obesity. There is considerable clinical heterogeneity and how much this reflects genetic versus environmental or stochastic factors is unclear. Forebrain interneurons originate from progenitors residing in the ventricular zone of the foetal ventral tel...

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Literature Corpus work: 3525c943-73a8-5350-8c65-d278de0a0f54
DOI: 10.64898/2026.05.21.26353723

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