Article

Single-nucleus RNA sequencing of human periventricular white matter in vascular dementia

2024-12-11

Abstract excerpt

Vascular dementia (VaD) refers to a variety of dementias driven by cerebrovascular disease and is the second leading cause of dementia globally. VaD may be caused by ischemic strokes, intracerebral hemorrhage, and/or cerebral small vessel disease, commonly identified as white matter hyperintensities on MRI. The mechanisms underlying these white matter lesions in the periventricular brain are poorly understood. In...

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Literature Corpus work: 571837e2-c4d7-505c-b63a-4940b4c25c9b
DOI: 10.1101/2024.12.06.627202

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