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A genome-wide CRISPR Screening identifies targets that drive Tolerogenic Dendritic Cells

2026-03-25

Abstract excerpt

Tolerogenic dendritic cells (TolDCs) are essential for immune tolerance and offer promise for treating autoimmune diseases. Despite the clinical evidence of their therapeutic potential, the key molecular pathways guiding their differentiation and tolerogenic phenotype remain elusive due to complex interactions identified in functional assays. Here we investigated the molecular profiles and regulatory programs unde...

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Literature Corpus work
55e8fbbe-a35b-5f28-bc29-858f054fedc3
DOI
10.64898/2026.03.23.713621
Open publication

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A genome-wide CRISPR Screening identifies targets that drive Tolerogenic Dendritic CellsDOI 10.64898/2026.03.23.713621
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