Article
Dendritic cells as gatekeepers of tolerance.
Seminars in immunopathology - 1 Feb 2017
Waisman Ari, Lukas Dominika, Clausen Björn E, Yogev Nir
Abstract excerpt
Dendritic cells (DC) are unique hematopoietic cells, linking innate and adaptive immune responses. In particular, they are considered as the most potent antigen presenting cells, governing both T cell immunity and tolerance. In view of their exceptional ability to present antigen and to interact with T cells, DC play distinct roles in shaping T cell development, differentiation and function. The outcome of the...
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