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Logical model of human tolerogenic dendritic cells and their participation in autoimmune disease

2023-08-23

Abstract excerpt

Tolerogenic dendritic cells (tolDC) regulate the immune response, several clinical trials focused on autoimmune diseases use tolDC to promote immune tolerance response and Treg activation. Here we built a logical model for the tolerization cellular process of dendritic cells using IL10. By combining literature knowledge, microarray gene expression, and key tolDC markers, we ensembled a logical model that describes...

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Literature Corpus work
b2611c3e-e8ed-541d-b436-a9faedc4ce06
DOI
10.1101/2023.08.22.554293
Open publication

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Logical model of human tolerogenic dendritic cells and their participation in autoimmune diseaseDOI 10.1101/2023.08.22.554293
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