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Article

Transcriptomic Analysis Identifies A Tolerogenic Dendritic Cell Signature.

Frontiers in immunology - 1 Jan 2021

Robertson Harry, Li Jennifer, Kim Hani Jieun, Rhodes Jake W, Harman Andrew N, Patrick Ellis, Rogers Natasha M

Abstract excerpt

Dendritic cells (DC) are central to regulating innate and adaptive immune responses. Strategies that modify DC function provide new therapeutic opportunities in autoimmune diseases and transplantation. Current pharmacological approaches can alter DC phenotype to induce tolerogenic DC (tolDC), a maturation-resistant DC subset capable of directing a regulatory immune response that are being explored in current...

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Identifiers

PMID: 34745103
DOI: 10.3389/fimmu.2021.733231
PMCID: PMC8564488

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