Article

piRNAs prevent runaway amplification of siRNAs from ribosomal RNAs and histone mRNAs

2020-06-16

Abstract excerpt

<h4>ABSTRACT</h4> Piwi-interacting RNAs (piRNAs) are a largely germline-specific class of small RNAs found in animals. Although piRNAs are best known for silencing transposons, they regulate many different biological processes. Here we identify a role for piRNAs in preventing runaway amplification of small interfering RNAs (siRNAs) from certain genes, including ribosomal RNAs (rRNAs) and histone mRNAs. In Caenor...

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Literature Corpus work: 55d24799-2d1f-5f21-9ccb-c842faada201
DOI: 10.1101/2020.06.15.153023

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