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Article

TOMM40 regulates hepatocellular and plasma lipid metabolism via an LXR-dependent pathway

2024-06-29

Abstract excerpt

<h4>ABSTRACT</h4> The gene encoding TOMM40 (Transporter of Outer Mitochondrial Membrane 40) is adjacent to that encoding APOE, which has a central role in lipid and lipoprotein metabolism. Human genetic variants near APOE and TOMM40 are strongly associated with plasma lipid levels, but a specific role for TOMM40 in lipid metabolism has not been established. Investigating this, we show that suppression of TOMM4...

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Identifiers and source

Literature Corpus work
55594378-712c-5633-b82b-d85ec840736e
DOI
10.1101/2024.06.27.600910
Open publication

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TOMM40 regulates hepatocellular and plasma lipid metabolism via an LXR-dependent pathwayDOI 10.1101/2024.06.27.600910
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