<span class="word">Cholesterol <span class="word">in <span class="word"><span class="changedDisabled">Mitochondrial <span class="word"><span class="changedDisabled">Diseases – <span class="word"><span class="changedDisabled">Friend <span class="word">or <span class="word"><span class="changedDisabled">Foe?

Abstract excerpt

Serving as central signalling organelles and hubs of metabolism, mitochondria are essential for cellular homeostasis. Mitochondrial disease can arise from mutations to nuclear or mitochondrial DNA, which result in disruptions to normal mitochondrial function. This generates a suite of rare disorders which are multi-systemic and often fatal. Variable tissue distribution of mitochondria, alongside high heterogeneity...

Topics

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• ATP Synthase and ATPases Research
• Autophagy in Disease and Therapy
• Bone and Bones
• Cholesterol and Lipid Metabolism
• Mitochondrial Diseases
• Mitochondrial Function and Pathology
• Mitochondrial Membrane Transport Proteins
• Peroxisome Proliferator-Activated Receptors

Identifiers and source

Literature Corpus work

37ae477e-d481-5944-bb4c-3203504d27ae

DOI

10.20944/preprints202603.0220.v1