Article

APOE <sup>ε4</sup> and exercise interact to influence systemic and cerebral risk factors for dementia

2022-03-03

Abstract excerpt

<h4>INTRODUCTION</h4> APOE ε4 is the strongest genetic risk factor for Alzheimer’s disease and related dementias (ADRDs) affecting many different pathways that lead to cognitive decline. Exercise is one of the most widely proposed prevention, and intervention strategies to mitigate risk and symptomology of ADRDs. Importantly, exercise and APOE ε4 affect similar processes on the body and brain. While both APOE...

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Literature Corpus work: 55531c68-089a-5648-83ac-da7486014538
DOI: 10.1101/2022.03.01.480612

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