Article

The effect of the APOE4 genotype on physiological and cognitive health in randomised controlled trials with an exercise intervention: a systematic review and meta-analysis

2023-11-23

Abstract excerpt

<title>Abstract</title> <bold>Background</bold> Alzheimer's disease is the most common form of dementia and has multiple causes, including modifiable and non-modifiable risk factors. Randomized controlled trials have investigated whether the strongest genetic risk factor for Alzheimer’s disease, APOE4, impacts the effectiveness of exercise on health outcomes. To date, there are no systematic reviews evaluating...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a617a06a-ef04-58da-868f-c64a81a4cb77
DOI: 10.21203/rs.3.rs-3288751/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The effect of the APOE4 genotype on physiological and cognitive health in randomised controlled trials with an exercise intervention: a systematic review and meta-analysisDOI 10.21203/rs.3.rs-3288751/v1Read

Does apolipoprotein E genotype moderate the association between physical activity and brain health? A systematic review and meta-analysisSemantic proximity Read

APOE ε4 and exercise interact to influence systemic and cerebral risk factors for dementiaSemantic proximity Read

Does APOE genotype moderate the relationship between physical activity, brain health and dementia risk? A systematic review.Semantic proximity Read

High-intensity Exercise and Cognitive Function in Cognitively Normal Older Adults: A Randomised Clinical TrialSemantic proximity Read

Patients with Alzheimer's disease who carry the APOE ε4 allele benefit more from physical exerciseSemantic proximity Read

How does Apolipoprotein E genotype influence the relationship between physical activity and Alzheimer’s disease risk? A novel integrative modelSemantic proximity Read

Interaction between physical exercise and APOE gene polymorphism on cognitive function in older people.Semantic proximity Read

Interaction between APOE4 status and lifestyle on brain and cognitive outcomes in cognitively unimpaired older adultsSemantic proximity Read

Walking to protect against cognitive decline: the role of APOE genotype and sex.Semantic proximity Read

APOE ε4 and exercise interact in a sex‐specific manner to modulate dementia risk factorsSemantic proximity Read

A cross-sectional examination of a family history of Alzheimer's disease and ApoE epsilon 4 on physical fitness, molecular biomarkers, and neurocognitive performanceSemantic proximity Read

APOEε4 impacts up-regulation of brain-derived neurotrophic factor after a six-month stretch and aerobic exercise intervention in mild cognitively impaired elderly African Americans: A pilot study.Semantic proximity Read