Article

μ-Opioid receptor transcriptional variants in the murine forebrain and spinal cord

2024-03-25

Abstract excerpt

<h4>Background</h4> Oprm1 , the gene encoding the μ-opioid receptor, has multiple reported transcripts, with a variable 3 region and many alternative sequences encoding the C-terminus of the protein. The functional implications of this variability remain mostly unexplored, though a recurring notion is that it could be exploited by developing selective ligands with improved clinical profiles. Here, we comprehensiv...

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Literature Corpus work: 553e4ec0-8f95-586c-a076-fbb5cc4f09cb
DOI: 10.1101/2024.03.20.585849

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