Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell types

13 Sept 2023

Abstract excerpt

With concurrent global epidemics of chronic pain and opioid use disorders, there is a critical need to identify, target and manipulate specific cell populations expressing the mu-opioid receptor (MOR). However, available tools and transgenic models for gaining long-term genetic access to MOR+ neural cell types and circuits involved in modulating pain, analgesia and addiction across species are limited. To address...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Stress, Anesthesia, and Immune Response
Share to Neuropeptides and Animal Physiology
Share to Pharmacological Receptor Mechanisms and Effects

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37704594
DOI: 10.1038/s41467-023-41407-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell typesPMID 37704594Read ↗

μ-Opioid receptor transcriptional variants in the murine forebrain and spinal cordSemantic proximity Read ↗

Enhancer AAVs for targeting spinal motor neurons and descending motor pathways in rodents and macaqueSemantic proximity Read ↗

Multi-omic profiling of human and mouse dorsal root ganglia enables targeted gene delivery to nociceptorsSemantic proximity Read ↗

Addiction associated N40D mu-opioid receptor variant modulates synaptic function in human neuronsSemantic proximity Read ↗

Spatial transcriptomics reveals distinct cell type dynamics following opioid dependence in mice with the common human variant in the μ-opioid receptor, Oprm1 A118GSemantic proximity Read ↗

Identification and Characterization of Seven New Exon 11-Associated Splice Variants of the Rat Mu Opioid Receptor Gene, OPRM1Semantic proximity Read ↗

Identification of genetic variations in μ opioid receptor in cats.Semantic proximity Read ↗

Immunohistochemical labeling of the mu opioid receptor carboxy terminal splice variant mMOR-1B4 in the mouse central nervous system.Semantic proximity Read ↗

The μ opiate receptor as a candidate gene for pain: Polymorphisms, variations in expression, nociception, and opiate responsesSemantic proximity Read ↗

Cis-regulatory elements driving motor neuron-restricted viral payload expression within the mammalian spinal cordSemantic proximity Read ↗

Cis-Expression Quantitative Trait Loci Mapping Reveals Replicable Associations with Heroin Addiction in OPRM1.Semantic proximity Read ↗

Identification and characterization of two new human mu opioid receptor splice variants, hMOR-1O and hMOR-1X.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.