Article
Identification of genetic variations in μ opioid receptor in cats.
Molecular pain - 1 Jan 2025
Sasaki Kazumasu, Hasegawa Junko, Ikeda Kazutaka, Ishikawa Tatsuya, Kasai Shinya
Abstract excerpt
μ-opioid receptor (MOP) plays a critical role in mediating opioid analgesic effects. Genetic variations, particularly those in the MOP gene (Oprm1), significantly influence individual variations in opioid efficacy and side effects across species, highlighting the need for pharmacogenomic research in human and veterinary contexts. This study aimed to identify single-nucleotide variations (SNVs) within Oprm1 in 100...
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