Article
Identification and characterization of two new human mu opioid receptor splice variants, hMOR-1O and hMOR-1X.
Biochemical and biophysical research communications - 21 Feb 2003
Pan Ying-Xian, Xu Jin, Mahurter Loriann, Xu Mingming, Gilbert Annie-Kim, Pasternak Gavril W
Abstract excerpt
The mouse gene encoding the mu opioid receptor, Oprm, undergoes extensive alternatively splicing, with 14 variants having been identified. However, only one variant of human mu opioid receptor gene (Oprm), MOR-1A, has been described. We now report two novel splice variants of the human Oprm gene, hMOR-1O and hMOR-1X. The full-length cDNAs of hMOR-1O and hMO-1X contained the same exons 1, 2, and 3 as the original...
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