Article
Overview of Genetic Analysis of Human Opioid Receptors.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Spampinato Santi M
Abstract excerpt
The human μ-opioid receptor gene (OPRM1 ), due to its genetic and structural variation, has been a target of interest in several pharmacogenetic studies. The μ-opioid receptor (MOR ), encoded by OPRM1 , contributes to regulate the analgesic response to pain and also controls the rewarding effects of many drugs of abuse, including opioids, nicotine, and alcohol. Genetic polymorphisms of opioid receptors are...
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