Article

Abrogating ALIX interactions results in stuttering of the ESCRT machinery

2019-03-14

Abstract excerpt

ESCRTs are cellular proteins that catalyze the fission of membranes and play an important role in biology of disease including cancer and infectious virus release 1 . ESCRT associated protein ALIX plays an essential role in HIV budding 2-4 , exosome release 5,6 , down regulation of G-protein coupled receptors 7 , cytokinesis 8,9 and multi vesicular budding 1 . The consensus view is that ALIX plays a role by...

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Literature Corpus work: 54cf9793-933e-5740-800d-dcf817384c18
DOI: 10.1101/576926

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