Article

PPM1D/Wip1 is amplified, overexpressed, and mutated in human Non-Hodgkin Lymphomas

2024-03-11

Abstract excerpt

<title>Abstract</title><p>Background Wip1, is a p53-dependent Ser/Thr phosphatase involved in the timely termination of DDR. The<italic>PPM1D</italic>gene encoding Wip1 is deregulated and thus gained an oncogene character in common human solid tumors and cell lines. This study assessed the oncogenic potential of the<italic>PPM1D</italic>gene in human NHL, the most common hematological malignancy worldwide. Methods...

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Literature Corpus work: 54cae1e7-f2b5-5aed-bd0a-ca8c5336c273
DOI: 10.21203/rs.3.rs-4021011/v1

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