Article
Wip1 phosphatase in breast cancer.
Oncogene - 20 Aug 2015
Emelyanov A, Bulavin D V
Abstract excerpt
Understanding the factors contributing to tumor initiation, progression and evolution is of paramount significance. Among them, wild-type p53-induced phosphatase 1 (Wip1) is emerging as an important oncogene by virtue of its negative control on several key tumor suppressor pathways. Originally discovered as a p53-regulated gene, Wip1 has been subsequently found amplified and more recently mutated in a significant...
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