Article

Co-targeting WIP1 and PARP induces synthetic lethality in hepatocellular carcinoma

2021-02-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Hepatocellular carcinoma (HCC) is one of the most fatal cancers. Due to limited strategies for effective treatments, patients with advanced HCC have a very poor prognosis. This study aims to identify novel druggable candidate genes for patients with HCC.<bold>Methods</bold>The role of WIP1 (wild type p53 induced protein phosphatase1) in HCC was analyzed in HCC cel...

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Literature Corpus work: 7aca2bc9-19e9-5ed7-9828-4133eb16b17f
DOI: 10.21203/rs.3.rs-238597/v1

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