Article

Potential Oncogenic Role of PRSS1 Identified by Whole Exome Sequencing in Glioma Primary Cell Lines

2026-04-01

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Glioblastoma (GBM) is the most common and aggressive adult primary brain malignancy, with poor survival and marked resistance to therapy. In pediatric patients, diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPG) with H3K27 alterations, are similarly lethal and completely refractory to therapy. These tumors present high inter and...

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Literature Corpus work: 542b90de-a472-534a-b268-34d52fbdd52d
DOI: 10.21203/rs.3.rs-8979829/v1

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