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Article

Multi-omics analysis of primary glioblastoma cell lines shows recapitulation of pivotal molecular features of parental tumors.

Neuro-oncology - 1 Feb 2017

Rosenberg Shai, Verreault Maïté, Schmitt Charlotte, Guegan Justine, Guehennec Jeremy, Levasseur Camille, Marie Yannick, Bielle Franck, Mokhtari Karima, Hoang-Xuan Khê, Ligon Keith, Sanson Marc, Delattre Jean-Yves, Idbaih Ahmed

Abstract excerpt

Background: Glioblastoma (GBM) is the deadliest primary brain cancer in adults. Emerging innovative therapies hold promise for personalized cancer treatment. Improving therapeutic options depends on research relying on relevant preclinical models. In this line we have established in the setting of the GlioTex project (GBM and Experimental Therapeutics) a GBM patient-derived cell line (GBM-PDCL) library. A...

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Identifiers

PMID: 27571888
DOI: 10.1093/neuonc/now160
PMCID: PMC5463853

Genes

PDCL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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