Article

Programmable nanobody circuits for cell selection

2026-02-23

Abstract excerpt

<h4>ABSTRACT</h4> Efficient and scalable isolation of specific cell populations remains a central bottleneck for genome engineering, pooled screening, and cell therapy manufacturing. Here, we present DASIT ( D estabilized-nanobody A ntigen S election and I dentification T ool), a protein-based circuit for antigen-specific cell selection. DASIT uses a destabilized nanobody fused to an antibiotic resistance pr...

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Literature Corpus work: 53e46422-9660-5cb9-b588-27280a1c2f13
DOI: 10.64898/2026.02.22.707289

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