Article

RNA-programmable cell type monitoring and manipulation in the human cortex with CellREADR

2024-12-06

Abstract excerpt

<h4>SUMMARY</h4> Reliable and systematic access to diverse cell types is necessary for understanding the organization, function, and pathophysiology of human neural circuits. Methods for targeting human neural populations are scarce and currently center on identifying transcriptional enhancers and engineering viral capsids. Here we demonstrate the utility of CellREADR, a programmable RNA sensor-effector technolog...

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Literature Corpus work: a8884cd2-e6e7-5669-943d-f57c0991faf7
DOI: 10.1101/2024.12.03.626590

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