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SynAuto-X: A Programmable CRISPR-dCas9 Circuit for Precision Inflammation Control in Autoimmune Disorders

2025-08-19

Abstract excerpt

<title>Abstract</title> <p>Autoimmune diseases represent a class of complex, multifactorial disorders characterized by the immune system’s aberrant recognition of self-antigens as foreign, leading to chronic inflammation, tissue damage, and progressive organ dysfunction. Despite advances in immunosuppressive pharmacology, current therapies remain largely non-specific, systemically cytotoxic, and incapable of achi...

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Literature Corpus work: 3ca120cb-c837-5e60-b3e3-7310caed5337
DOI: 10.21203/rs.3.rs-7399233/v1

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