Article

CRISPR-based Genome Editing of a Diurnal Rodent, Nile Grass Rat ( <i>Arvicanthis niloticus)</i>

2023-08-23

Abstract excerpt

Diurnal and nocturnal mammals have evolved distinct pathways to optimize survival for their chronotype-specific lifestyles. Conventional rodent models, being nocturnal, may not sufficiently recapitulate the biology of diurnal humans in health and disease. Although diurnal rodents are potentially advantageous for translational research, until recently, they have not been genetically tractable. Here, we address this...

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Literature Corpus work: 53dfc336-4549-54df-b65a-fda3ccbd5c8a
DOI: 10.1101/2023.08.23.553600

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