Article

Derivation, Characterizations, and Applications of Rabbit Haploid Embryonic Stem Cells

2025-11-06

Abstract excerpt

Haploid embryonic stem cells (haESCs), which contain a single set of chromosomes, provide powerful systems for investigating gene function and creating gene-edited animal models. haESCs have been derived from several mammalian species including human, mouse and rats, yet not from rabbits. Here, we report the derivation of parthenogenetic haESCs of rabbit (rbPhESCs) using an optimized culture medium. These cells ma...

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Literature Corpus work: f950a137-b50d-52fe-996e-acb399a21ade
DOI: 10.1101/2025.11.05.686447

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