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Article

Modeling human disease in rodents by CRISPR/Cas9 genome editing.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2017

Birling Marie-Christine, Herault Yann, Pavlovic Guillaume

Abstract excerpt

Modeling human disease has proven to be a challenge for the scientific community. For years, generating an animal model was complicated and restricted to very few species. With the rise of CRISPR/Cas9, it is now possible to generate more or less any animal model. In this review, we will show how this technology is and will change our way to obtain relevant disease animal models and how it should impact human health.

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Share to Animals, Genetically Modified
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28677007
DOI: 10.1007/s00335-017-9703-x
PMCID: PMC5569124

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