Article

Non-additive polygenic models improve predictions of fitness traits in three eukaryote model species

2020-07-15

Abstract excerpt

<h4>ABSTRACT</h4> To describe a living organism it is often said that “the whole is greater than the sum of its parts”. In genetics, we may also think that the effect of multiple mutations on an organism is greater than their additive individual effect, a phenomenon called epistasis or multiplicity. Despite the last decade’s discovery that many disease- and fitness-related traits are polygenic, or controlled by m...

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Literature Corpus work: 53a5e9b8-f003-51b3-b021-26eaedac62de
DOI: 10.1101/2020.07.14.194407

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