Article

Finding the Sources of Missing Heritability Using the Additive Epistatic Interaction Model: A Simulation Study

2022-03-11

Abstract excerpt

<title>Abstract</title> <p>Objective Thousands of Genome-Wide Association Studies (GWAS) have been carried out to pinpoint genetic variants associated with complex disease. However, the proportion of phenotypic variance which can be explained by the identified genetic variants is relatively low. Thus, it is desirable to propose new computational models to explain the “missing heritability” problem. Results Here...

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Literature Corpus work: 36a8de24-6a1b-54a3-9c14-00f66378750d
DOI: 10.21203/rs.3.rs-1323648/v1

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