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Article

Rapid Epistatic Mixed Model Association Studies by Controlling Multiple Polygenic Effects

2020-03-05

Abstract excerpt

<h4>Summary</h4> We have developed a rapid mixed model algorithm for exhaustive genome-wide epistatic association analysis by controlling multiple polygenic effects. Our model can simultaneously handle additive by additive epistasis, dominance by dominance epistasis and additive by dominance epistasis, and account for intrasubject fluctuations due to individuals with repeated records. Furthermore, we suggest a si...

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Literature Corpus work
f984de3a-2d83-588f-bdcc-f9193352fb22
DOI
10.1101/2020.03.05.976498
Open publication

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Rapid Epistatic Mixed Model Association Studies by Controlling Multiple Polygenic EffectsDOI 10.1101/2020.03.05.976498
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