Article

MosCoverY: a new method to estimate mosaic Loss of Y chromosome from NGS sequencing coverage data

2024-11-11

Abstract excerpt

<h4>ABSTRACT</h4> Mosaic loss of the Y chromosome (mLOY) is the most common somatic event in men, strongly associated with aging and various health conditions. Current methods for detecting mLOY primarily rely on DNA genotyping arrays. Here, we present MosCoverY, a novel method for estimating mLOY from NGS sequencing data that can be applied to both exome and genome sequencing. MosCoverY addresses the challenges p...

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Literature Corpus work: 53a4f799-4f96-5896-9232-3816bb785f2c
DOI: 10.1101/2024.11.11.24317095

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