Article

MADloy: Robust detection of mosaic loss of chromosome Y from genotype-array-intensity data

2019-09-10

Abstract excerpt

Accurate protocols and methods to robustly detect the mosaic loss of chromosome Y (mLOY) are needed given its reported role in cancer, several age-related disorders and overall male mortality. Intensity SNP-array data have been used to infer mLOY status and to determine its prominent role in male disease. However, discrepancies of reported findings can be due to the uncertainty and variability of the methods used...

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Literature Corpus work: 49fb70e3-9890-5235-90ea-b31caec404e5
DOI: 10.1101/764845

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