Article

Spatially Integrated Multi-Omics reveals the Multicellular Landscape of Progenitor-Driven Glioblastoma Progression

2026-02-28

Abstract excerpt

Glioblastoma is the most lethal primary brain tumor, driven by complex interactions between plastic malignant cells and a diverse tumor microenvironment. Despite advances in single-cell profiling, how genomic drivers and the tumor microenvironment interact to determine tumor progression and patient survival remains poorly understood. While cellular states have been cataloged, the multi-cellular logic coordinating...

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Literature Corpus work: 8f7caa0f-81c5-54f2-a4b9-917c1d75c152
DOI: 10.64898/2026.02.26.708154

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